Working Group 4

Data science and data management

Objectives and Activities

The primary focus of WG4 is to create a knowledge-sharing community among experts and people interested in the bioinformatic analysis of the gut microbiota within in vitro systems. This encompasses the identification, organisation and cataloguing of FAIR microbiome data sources, resources and tools related to multi-omics data from the gut. After identification, we aim to evaluate each tools suitability for studying in vitro models of the gut and provide guidance to users.

Working group leaders

Thomas C. A. Hitch

WG4 leader
University Hospital of RWTH Aachen, Aachen

Enrique Carrillo de Santa Pau

WG4 VCo-leader
IMDEA Nutrition, UAM+CSIC, Madrid

Tasks

Task 4.1.

Create FAIR catalogues for the gut omics data.

Task 4.2.1.

Review in silico approaches for multi-omic data analysis

Task 4.2.2.

Benchmark in silico approaches for gut microbiota analysis

Task 4.3.

Develop training materials: design, organize, and implement training material for gut data

Deliverables

D4.1

A public catalogue of open data and bioinformatics resources. Due at month 15.

D4.2

Report on state-of-the-art data integration methods for gut microbiome data. Due at month 24.

D4.3

Publication with the findings and summarizing the results from D4.1-D4.2. Due at month 36.

D4.4

Training materials and subsequent revisions. Due at month 24-36.

Working group meetings

COST

COST (European Cooperation in Science and Technology) is a funding agency for research and innovation networks. Our Actions help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation. (www.cost.eu)

COST Action CA23110

Scientific literature is shedding light on the centrality of GI for human health and wellbeing. Indeed, the physiologic effects of nutrients, bioactives and even toxic compounds (including foodborne pathogens) are mediated by their absorption rate in the intestine and by their interaction with gut microbiota and its host ecosystem. Testing food, feed, supplements or drugs in clinical studies gives rise to ethical issues, and the transferability of animal data across species is often problematic because of differences in physiology, metabolism and chemical susceptibilities.

MoU
062/22

CSO Approval Date
27/05/2022

Start Date
06/10/2022

End Date
05/10/2026

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